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Role of CGA in type2 diabetes and cardiovascular disease CGA contributes to the metabolism of glucose by promoting glucose uptake in both insulinsensitive and noninsulinsensitive adiposity (Gkcen & anlier, 2019) and also increases insulin secretion, decreases insulin tolerance, and activates or inhibits the body's enzyme activity to promote glucose metabolism, lowering blood glucose levels, and treating diabetes by reducing insulin tolerance (Jin et al., 2015)

(2) The first isolation of the peptide was carried out in 1920, followed by its structure discovery in the 1950s

Protects skin cells and fibroblasts from oxidative stress, a significant cause of aging

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